Endocrine Abstracts

The treatment of orbitopathy in the course of Graves’ disease (GO, Graves’ Orbitopathy) still remains a serious therapeutic challenge. Modification of risk factors is considered to be the most important and the most effective method of treatment of benign GO. Treatment with intravenous glucocorticosteroid preparations remains the first-line therapy for moderate- to severe GO but is insufficient in some patients. Radiotherapy has been used in active GO therapy for d...

Background: Polycystic ovary syndrome (PCOS) is a condition affecting up to 20% of reproductive-aged women. PCOS is associated with obesity and serious metabolic complications. There is a lack of research evaluating differences in metabolic complications between hyperandrogenic physically active and inactive individuals.Objective: We used a cross-sectional study to compare the risk of obesity, metabolic syndrome, visceral adipose index, and insulin resis...

The Trabecular Bone Score (TBS) has recently been developed through the grayscale textural analysis of Dual-Energy X-ray Absorptiometry (DXA) images. Due to its capability to evaluate the microarchitectural texture of bone, TBS proves valuable in the assessment of bone quality. While the clinical relevance of TBS has been partially confirmed in relation to hormonal disorders, there is currently a lack of precise data regarding its application during specific phases of treatmen...

Introduction: Acromegaly is a rare, chronic and progressive disease caused by a pituitary adenoma. Excessive secretion of growth hormone (GH) and insulin-like growth factor-I (IGF-I) leads to cell proliferation and differentiation, which results in changes in external appearance and causes various systemic complications. Elevated levels of GH and IGF-I are also thought to promote the development of cancer and some studies have shown that acromegaly is a disease with a high ris...